Science

Species & Toxins

Of the over 2,000 known cyanobacteria species, about 40 genera produce various toxins.

☠️Toxin Categories

🫀

Hepatotoxins

Attack the liver

Microcystin, Nodularin, Cylindrospermopsin
🧠

Neurotoxins

Attack the nervous system

Anatoxin-a, Saxitoxin, BMAA
🖐️

Dermatotoxins

Irritate skin and mucous membranes

Lyngbyatoxin, Aplysiatoxin

🔬Key Cyanotoxins

Microcystin

Hepatotoxin

Inhibits protein phosphatases in the liver, leading to cell structure destruction.

MicrocystisPlanktothrixAnabaena
  • Nausea, vomiting, diarrhea
  • Abdominal pain
  • Liver damage
  • Possibly carcinogenic

Anatoxin-a

Neurotoxin

Binds to acetylcholine receptors, causing overstimulation then blockade.

AnabaenaAphanizomenonOscillatoria
  • Muscle tremors, cramps
  • Respiratory distress
  • Salivation
  • Rapid death possible

Cylindrospermopsin

Hepato-/Cytotoxin

Inhibits protein synthesis, damages liver, kidneys and other organs.

CylindrospermopsisAphanizomenon
  • Delayed onset
  • Liver and kidney damage
  • General malaise

Saxitoxin

Neurotoxin

Blocks sodium channels, prevents nerve impulse transmission.

AnabaenaAphanizomenonLyngbya
  • Numbness
  • Muscle weakness, paralysis
  • Respiratory arrest

📋Guidelines & Limits

ToxinDrinking Water (WHO)Recreational WaterSource
Microcystin-LR1 µg/L10-20 µg/LWHO 2020
Cylindrospermopsin0.7 µg/L6 µg/LWHO 2020
Anatoxin-a30 µg/L60 µg/LWHO 2020
Saxitoxin3 µg/L30 µg/LWHO 2020

WHO guidelines are recommendations. National limits may vary.

🦠Common Toxin-producing Genera

🦠

Microcystis aeruginosa

High Risk
Microcystin

Freshwater, worldwide

  • Colonial aggregates
  • Floats via gas vesicles
  • Most common bloom former
🦠

Anabaena / Dolichospermum

High Risk
Anatoxin-aMicrocystinSaxitoxin

Freshwater, temperate to tropical

  • Filamentous with heterocysts
  • Nitrogen-fixing
  • Multiple toxins
🦠

Planktothrix rubescens

Medium Risk
Microcystin

Deep, cool lakes

  • Reddish color
  • Mid-depth habitat
  • Can bloom in winter
🦠

Nodularia spumigena

High Risk
Nodularin

Brackish water, Baltic Sea

  • Baltic Sea specialist
  • Forms surface foam
  • Summer blooms
🦠

Cylindrospermopsis raciborskii

High Risk
Cylindrospermopsin

Originally tropical, spreading north

  • Climate change beneficiary
  • Invasive in Europe
  • Delayed toxicity
🦠

Aphanizomenon flos-aquae

Medium Risk
Anatoxin-aSaxitoxin

Freshwater, worldwide

  • Grass-like flakes
  • Nitrogen-fixing
  • Not all strains toxic

📚 Sources & References

[1] WHO (2020). Cyanobacterial toxins: Microcystins.

[2] Chorus, I. & Welker, M. (2021). Toxic Cyanobacteria in Water, 2nd Edition.

[3] Buratti, F. M. et al. (2017). Cyanotoxins: producing organisms, occurrence, toxicity.